Optical recognition for blood stream studies

Development of an optical recognition system with microfluidics manipulation for real-time analysis of blood samples, drug delivery inside artificial arteries and 3D reconstruction of microfluidics, fluid analysis and particle tracking. It also includes the development of artificial transparent arteries for medical studies.

Here you can find some extra detailed information regarding our work presented at PAHCE 2013, one related to Artificial Arteries and the other one related to Living-microorganism biomicrosystems.

>> Get more info about our young researchers in this project

>> Get more information about how we manage to produce this projects in six months with untrained researchers (Nature Trade-secrets blog)

Study of mixing conditions for drug delivery inside artificial muscular arteries

M.C. Delgado, D. Clavijo, Z.I. Gonzalez, S.M.Segura, J.F. Osma

CMUA, Department of Electrical and Electronics Engineering.Universidad de los Andes, Bogota, Colombia

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Abstract -This work studied the mixing behavior of a foreign substance entering into the blood stream. For this study, artificial muscle arteries were designed and manufactured with diameters from 75 μm to 930 μm. The interaction of substances such as water, blood and serum was studied. After the devices were fabricated, the study was conducted using a characterization platform that consisted on a precision micropump module and an optical system which delivers high-res frame by frame information, and realtime moving microscopic samples.

Keywords – Artificial artery, drug delivery, microfluidics dynamics

Concept design for a novel confined-bacterial-based biosensor for water quality control

C. A. Hernández1, L. N. Gaviria2, S. M. Segura1, J. F. Osma1

1CMUA, Department of Electrical and Electronics Engineering.
2Department of Biological sciences.
Universidad de los Andes, Bogota, Colombia

Abstract - The care and protection of world resources propose nowadays new challenges and compromises, which require a rapid action to assure future availability. Constant efforts have been made to control changes that might affect life; continuous surveillance plays a key-role on environmental conservation and different methods had been used to determine the quality of such resources. The aim of the current research is the design of an easy to use, yet cheap, biosensor, based on electrical properties of different microorganisms, confined in a suitable microestructure.

Keywords – Biotechnology, Biosensors, Bacteria, Microsystems, Water

If you wonder how artificial arteries were produced by our group do not loose the opportunity to see the real deal. CMUA is proud to present the behind the scenes of Artificial Arteries.

road to pahce with artificial arteries-1 - copia

Do you want to know how the technology of living-microorganism microsystems was made possible do not loose the opportunity to see CMUA's behind-the-scene of Living microorganism biomicrosystems.

living microorganism biomicrosystems

This is how real blood (mainly red-blood cells) runs inside the artificial arteries. The one shown in the following image has a width of 100 um.

Finally, if you have a web browser that supports Flash videos (not compatible with Android), you can see a couple of videos from real samples processed by our group. (Top) Mixture of blood stream and serum inside an artificial artery. (Bottom) An intentionally produced blood clot inside an artificial artery.

Click to download in FLV format (5.88MB)

Click to download in FLV format (102.61kB)

Centro de Microelectrónica Universidad de los Andes -